JuniperPublishers-Global Journal of Nanomedicine

Global Journal of Nanomedicine-Juniper publishers Introduction Drug carrier systems (dendrimers, liposomes, polymers, micelles and metal nanoparticles) are promising tools in the treatment of many diseases by providing decreased drug toxicity to healthy cells and tissues and meanwhile increasing the drug bio-availability in targeted cites [ 1 ]. Liposomes are artificially formed vesicles consist of lipids that enclosed as spherical, non- aqueous compartment [ 2 ]. Liposomes have been widely used as a model system of a cell membrane, and more recently have been developed for the controlled release of pharmaceuticals and macromolecules. Liposomes can increase the tolerance of active compounds by lowering the active toxicity of its encapsulated contents, [ 3 ] whilst also opening up the possibility of transporting pharmaceuticals into the tissue of whim in a controlled manner [ 4 ]. After administration to the blood stream, liposomes are mainly taken up in by the liver and spleen [ 5 ] th...

  Global Journal of Nanomedicine-Juniper publishers Introduction Nanomedicine is different from the conventional approaches in sense that conventional medicine's approach is based on a response to problems at a tissue level and by the time that symptoms become apparent to patient or clinician, the disease may be often at an advanced stage. Conventional technology may also rely more on the use of sophisticated and expensive medical tools, machines, robots, minimally invasive devices, and implants. However, in nanomedicine, the goal is to detect changes and problems on the molecular and cellular levels and to treat them before they spread out [ 1 ]. Cancer is the first leading cause of diseased associated death in China [ 2 ] and second leading cause of death in the United States [ 3 ] in recent years. The recent treatment modalities for tumors which mainly include surgery, chemotherapy, radiotherapy, and immunotherapy, among which drug treatment is still most widely used therapeutic...