Controlling Amphiphilic Functional Block Copolymers’ Self-Assembly: From Structure to Size


Authored by Fei Liu

Nanostructure of self-assembled particles, such as micelles and polymersomes play an important role in drug delivery, especially in tumor therapy. Particles with various structures and proper sizes (20~500 nm) are regarded as perfect candidates for controlled drug delivery due to controllable size that benefits the extended permeation and retention (EPR) and high payload that increases drug delivery efficiency. In this review, we summarized recent representative studies in controlling the size and structure of Amphiphilic block copolymers self-assembled particles with pH- and temperature responsiveness.

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